Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study.

BACKGROUND AND PURPOSE Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke. METHODS We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients. RESULTS We found no association of hypoperfusion (relative cerebral blood flow <0.51) with early (<6 hours) or delayed (<72 hours) hyperglycemia, or hemispheric lateralization. CONCLUSIONS Insular cortex hypoperfusion <6 hours after stroke onset was not associated with hyperglycemia.